SiroBoon (Sirolimus)

SiroBoon is an oral tablet prescribed among patients undergoing kidney transplant. Whenever an organ transplant surgery happens, the immune system tries to attack the new organ and rejects it. This medicine helps regulate the response of the immune system so that it starts accepting the transplanted organ as its own instead of attacking/rejecting the same.

The treatment period usually varies among patients as per their overall medical conditions, requirements for treatment, and response to the drug.

How does the SiroBoon Tablet work?

The action mechanism of this drug relies on its major active ingredient – Sirolimus. It belongs to an immunosuppressant class of drugs known for regulating the response of the immune system, thus preventing rejection of kidney transplants.

After the kidney transplant, the immune system’s response activates and considers the transplanted organ as foreign. This leads to rejection. Hereby, Sirolimus blocks the activation and proliferation of T-cells to reduce the risk of organ rejection. Such targeted action helps in minimizing complications and allows the body to accept new organs.

Uses and Indications

This drug is primarily used for preventing kidney transplant rejection. However, it could be indicated among patients who have undergone heart or liver transplants to ensure acceptance of the transplanted organ.

It may be advised with combination medicines (other immunosuppressant’s) for enhancing effectiveness. Overall, this drug aims at maintaining a stable environment by minimizing damage mediated by the immune system.

Benefits of SiroBoon

1. Reduces risk of kidney transplant rejection.
2. Ensures optimal functions of the transplanted organ for a longer span.
3. Flexible dosages to choose from as per the patient’s requirements.
4. Comprehensive approach against kidney transplant rejection.
5. Allows patients to resume routine activities confidently.

Recommended dosage of SiroBoon Tablets

SiroBoon tablet is available in very mild dosage strength as 1 mg, 2 mg, 3 mg and 5 mg. This medicine is prescribed according to the patient’s age, body weight, pre-existing medical conditions (if any) and immune response levels. Low to highly mild dosages are suggested gradually, only if the lower dosage strength is falling short of delivering the desired effectiveness.

• SiroBoon 1 mg (Beginner dosage suggested to start immediately after transplant)
• SiroBoon 2 mg (Intermediate dosage adjusted as per the patient’s response and blood sirolimus levels)
• SiroBoon 3 mg (Suggested when 1 mg & 2 mg are not enough)
• SiroBoon 5 mg (Mild dosage advised when all of the low dosage strengths are not working out as expected)

How to use SiroBoon tablets?

SiroBoon dosage should be taken as indicated by the physician. This medicine is typically advised for once-daily use, right after the surgery to regulate the response of the immune system. Make sure to take the dosages timely, according to your treatment schedule to ensure optimal benefits.

Swallow one whole SiroBoon tablet with a glass of water, with or without food. Don’t use this medicine by crushing, chewing, or breaking. Try to take the dosage at a fixed time daily to sustain efficacy in the bloodstream.

Missed dose: Try not to miss your dosages else it’ll take longer for your body to regulate the response of the immune system. However, if a dose is missed, use it right when you remember. Avoid making up for missed doses if the next dosage is scheduled anytime soon.

Overdose/Misuse: Avoid using more or less than the suggested dosage strength, altering the frequency or number of pills per dose. If misused, serious side effects could occur in no time. Seek medical attention immediately if any non-favourable circumstances arise.

Side Effects of SiroBoon

Just like any other medicines, certain SiroBoon side effects exist too. Typically, these mild to moderate-intensity symptoms show up. They’ll supposedly subside as the body adjusts with Sirolimus.

• Nausea
• Fever
• Diarrhea
• Abdominal pain
• Rise in blood lipid levels
• Swelling or joint pain
• Increased exposure to infections
• Slow healing of wounds
• Urinary tract infection
• Low blood platelet count (anaemia)

Contact your physician if any side effects worsen or any of these rare yet severe symptoms appear:

• Pulmonary complications
• Increase in cholesterol levels
• High triglyceride levels
• Critical allergic reactions

Warnings & Safety Advice

• Check all the ingredients listed on the product label to ensure you’re not allergic to any of them before starting your treatment. Inform the doctor if an allergy is known towards any, particularly Sirolimus.
• This drug does not cause dizziness or affect vision. So, it is safe to drive or use machinery right after the dose.
• Don’t drink alcohol during your treatment with this medicine.
• Inform the doctor if you are pregnant or breastfeeding before initiating treatment with this drug.
• Tell your doctor if you have any critical health issues pre-existing.
• Complete the full course of treatment. Don’t stop your treatment abruptly else negative effects shall occur.

Conclusion

SiroBoon tablet is a valuable treatment among kidney transplant patients. This Sirolimus composition is potent enough to regulate the immune system’s response and prevent organ rejection. Thus, it allows the body to accept the transplanted organ soon. It is often advised with combination immunosuppressant’s as a comprehensive approach for preventing organ rejection in kidney transplant patients.

FAQs

What is the Sirolimus brand name?

Sirolimus is sold under different brand names. The one manufactured by Kachhela Medex Pvt. Ltd. Is marketed as SiroBoon.

What is the use of SiroBoon Tablet?

SiroBoon tablet is mainly used for preventing rejection of kidney transplants among patients who just had organ transplant surgery. It could be advised among patients who have had heart or liver transplants for the body to stop considering transplanted organs as foreign and accept them soon.

Can SiroBoon be taken with other medications?

Yes, it can be indicated as combination therapy with other immunosuppressive medications to enhance their effectiveness.

What are the common side effects of SiroBoon?

Oedema (swelling), nausea, headache, abdominal pain, increased risk of infections, low blood platelet count, etc are the common side effects of SiroBoon tablets. Consider visiting the healthcare provider if these symptoms persist for a prolonged duration in an adverse nature.

Can pregnant or breastfeeding women use SiroBoon?

Limited research proves the efficacy of this drug during pregnancy or breastfeeding. Hence, it is not advised among pregnant and breastfeeding women. Talk to your doctor if you are a woman with such medical conditions before starting treatment with this drug.

How should I store SiroBoon?

Store SiroBoon between 15 and 25 Degrees Celsius, away from moisture and high temperatures. Keep it out of reach and sight of children and pets.