Mesalazine 1gm Suppository

What is Mesalazine 1gm Suppository?

Mesalazine 1gm Suppository is a medication designed to deliver the active ingredient Mesalazine directly to the rectal area. It is primarily used to treat inflammatory bowel conditions such as ulcerative colitis and Crohn's disease affecting the lower bowel. Manufactured by Sun Pharmaceutical Industries Ltd, this suppository provides targeted relief through local anti-inflammatory action.

Developed for patients requiring effective management of their symptoms, Mesalazine 1gm Suppository works by reducing inflammation and irritation in the rectum and distal colon. This localized treatment helps improve symptoms and supports intestinal healing while minimizing systemic side effects.

Uses of Mesalazine 1gm Suppository

• Treatment of mild to moderate ulcerative colitis affecting the rectum and lower colon
• Management of proctitis symptoms associated with ulcerative colitis
• Supportive therapy for Crohn's disease involving the rectal area
• Reducing inflammation and promoting mucosal healing in the distal colon
• Maintaining remission in ulcerative colitis patients

How Mesalazine 1gm Suppository Works

Mesalazine 1gm Suppository delivers Mesalazine directly to the inflamed mucosa of the rectum and lower colon where it exerts a topical anti-inflammatory effect. It inhibits the production of inflammatory chemicals such as prostaglandins and leukotrienes, which are responsible for tissue inflammation and damage in ulcerative colitis and Crohn's disease. This targeted approach helps reduce symptoms like bleeding, pain, and urgent bowel movements by calming inflammation at the source.

Benefits of Mesalazine 1gm Suppository

• Provides localized treatment reducing systemic side effects
• Supports rapid relief from rectal inflammation and discomfort
• Helps heal ulcerations within the lower colon and rectum
• Maintains disease remission in chronic inflammatory bowel conditions
• Easy to use with once daily administration

Dosage and Administration

Mesalazine 1gm Suppository is usually administered once daily, preferably at bedtime, to maximize contact time with the affected tissues during rest. The suppository should be inserted gently into the rectum after emptying the bowels for optimal absorption. Patients should follow their healthcare provider's instructions carefully and complete the prescribed course even if symptoms improve. Do not break or chew the suppository.

Who Should Use Mesalazine 1gm Suppository?

This medication is suitable for adults and adolescents diagnosed with active ulcerative colitis or Crohn’s disease involving the rectal area. It is recommended for patients whose symptoms include rectal bleeding, inflammation, or pain caused by distal colon inflammation. Use under medical supervision is advised for optimal disease management.

Who Should Avoid Mesalazine 1gm Suppository?

Mesalazine 1gm Suppository is contraindicated in patients with known hypersensitivity to Mesalazine or any of its components. It should be avoided in individuals with severe renal impairment or those who have had allergic reactions to similar salicylate medications. Pregnant or breastfeeding women should consult their healthcare provider before use.

Side Effects

• Rectal irritation or discomfort
• Burning sensation at the site of insertion
• Abdominal pain or cramps
• Diarrhea
• Headache
• Nausea
• Dizziness
• Rare allergic reactions such as rash or itching

Safety Advice

• Inform your doctor if you have kidney problems or a history of allergies
• Use the suppository exactly as prescribed without skipping doses
• Avoid using other rectal products at the same time unless directed
• Report any unusual symptoms like severe abdominal pain or persistent diarrhea promptly
• Do not discontinue therapy abruptly without consulting your physician

Drug Interactions

• Concurrent use with other salicylates may increase side effects
• Mesalazine may interact with certain blood thinners such as warfarin
• Use caution when taken with medications affecting kidney function
• Inform your healthcare provider about all medicines including over-the-counter drugs

Storage Instructions

Store Mesalazine 1gm Suppository at room temperature between 15°C and 30°C in a dry place away from direct sunlight. Keep the suppositories in their original packaging until use. Keep out of reach of children. Do not freeze or expose to excessive heat to maintain effectiveness.

Where to buy Mesalazine 1gm Suppository in Canada?

If you are looking to buy Mesalazine 1gm Suppository in Canada, it is available through licensed pharmacies with a valid prescription. Many online Canadian pharmacies also stock this medication, ensuring convenient access for patients requiring treatment for inflammatory bowel disease. Always purchase from reputable sources to guarantee product authenticity and safety.

Frequently Asked Questions (FAQ)

Is Mesalazine 1gm Suppository available in Canada?

Yes, Mesalazine 1gm Suppository is available in Canada through prescription and can be obtained at local pharmacies or authorized online vendors.

What is the price of Mesalazine 1gm Suppository in Canada?

The price may vary depending on the pharmacy and insurance coverage; consult local pharmacies for specific rates and possible discounts.

What happens if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is near the time for your next dose. Do not double the dose to catch up.

Where can I find Mesalazine 1gm Suppository for sale?

It can be purchased at licensed pharmacies or reputable online Canadian pharmaceutical stores with a prescription.

Can I use Mesalazine 1gm Suppository during pregnancy?

Consult your healthcare provider before use during pregnancy to weigh potential benefits and risks.

Are there any dietary restrictions while using Mesalazine 1gm Suppository?

No specific dietary restrictions are required, but maintaining a balanced diet is recommended for better health.

How long does it take to see effects from Mesalazine 1gm Suppository?

Many patients notice symptom improvement within a few days to weeks; however, complete healing may take longer. Follow your doctor's advice for duration.

Conclusion

Mesalazine 1gm Suppository is a targeted, effective treatment option for managing ulcerative colitis and Crohn’s disease localized to the rectum and distal colon. Its local anti-inflammatory action offers symptom relief, mucosal healing, and maintenance of remission, improving quality of life for patients. Manufactured by Sun Pharmaceutical Industries Ltd, this suppository is a trusted medication available across Canada through licensed providers. Proper use, adherence to medical advice, and regular monitoring ensure the safe and effective use of Mesalazine 1gm Suppository.