What is Dimethyl fumarate 120 mg?
Dimethyl fumarate 120 mg is a prescription medicine primarily used in the management of Multiple Sclerosis (MS). Manufactured by Sun Pharmaceutical Industries Ltd, this medication is designed to help patients by modifying the immune system response to reduce the frequency of MS flare-ups and slow the progression of the disease. It is an oral therapy option that has gained recognition for its role in treating relapsing forms of MS.
Available in 120 mg dosage, this formulation suits patients starting dimethyl fumarate treatment or those who require a staged dosing schedule. Its approval and use in Canada provide patients with an advanced option in managing their condition under medical guidance.
Uses of Dimethyl fumarate 120 mg
- Treatment of relapsing forms of Multiple Sclerosis (MS)
- Reduction of frequency of MS relapses (flare-ups)
- Slowing the progression of physical disability associated with MS
- Modulation of immune system to manage inflammation in MS
How Dimethyl fumarate 120 mg Works
Dimethyl fumarate works by activating the Nrf2 pathway, which helps to protect nerve cells from damage caused by inflammation and oxidative stress commonly seen in Multiple Sclerosis. It also exhibits immunomodulatory effects by reducing the activity of immune cells that attack the nervous system. This combined mechanism helps in reducing the inflammatory response and potentially limits the damage to nerve fibers, which translates into slower progression of symptoms and fewer relapses.
Benefits of Dimethyl fumarate 120 mg
- Helps lower the frequency of MS relapses
- May slow disability progression in MS patients
- Oral administration offers convenience compared to injectable therapies
- Supports antioxidant responses protecting nerve cells
- Well-studied and widely prescribed by healthcare professionals
Dosage and Administration
The recommended starting dose typically involves taking Dimethyl fumarate 120 mg capsules twice daily. Dosage may be gradually increased as directed by a healthcare provider. Patients should follow their physician's instructions carefully and avoid modifying doses without medical advice. It is important to take this medication with food to reduce gastrointestinal side effects and maintain consistent timing for doses each day to optimize treatment effect.
Who Should Use Dimethyl fumarate 120 mg?
This medication is intended for adults diagnosed with relapsing forms of Multiple Sclerosis. It is especially suitable for patients requiring a therapy that can be administered orally and who have been evaluated by a neurologist or MS specialist. Patients starting MS treatment or changing from another disease-modifying therapy under medical supervision may be prescribed this formulation.
Who Should Avoid Dimethyl fumarate 120 mg?
Dimethyl fumarate should be avoided by individuals with known hypersensitivity to any ingredient of the medication. Patients with severe liver impairment or active infections should consult their healthcare provider before use. It is not recommended for pregnant or breastfeeding women unless clearly advised by a physician due to limited safety data. Individuals with a history of serious allergic reactions or specific blood abnormalities must use caution and follow medical advice.
Side Effects
- Flushing (redness and warmth of the skin)
- Gastrointestinal discomfort (nausea, diarrhea, abdominal pain)
- Headache
- Dizziness
- Lowered white blood cell count (lymphopenia)
- Increased risk of infections
- Elevated liver enzymes
- Rash or itching
- Rare allergic reactions
Safety Advice
- Inform your doctor about all existing medical conditions
- Regular blood tests are recommended to monitor white blood cell counts
- Report any signs of infection such as fever or sore throat promptly
- Avoid sudden discontinuation of treatment without consulting a healthcare professional
- Use contraception effectively during treatment and for a specified period after stopping
- Store the medicine out of reach of children
- If you experience serious side effects, seek immediate medical attention
Drug Interactions
- Other immunosuppressive therapies may increase infection risk
- Drugs metabolized by the liver may interact altering effectiveness
- Live vaccines should be avoided during treatment
- Consult your doctor before combining with any new medication
Storage Instructions
Dimethyl fumarate 120 mg capsules should be stored at room temperature, away from excessive heat and moisture. Keep the medication in its original packaging until use to protect from light. Ensure the container is tightly closed and keep out of reach of children and pets.
Where to buy Dimethyl fumarate 120 mg in Canada?
Dimethyl fumarate 120 mg can be purchased through licensed Canadian pharmacies with a valid prescription. Patients are advised to buy from reputable sources to ensure product authenticity and safety. Many healthcare providers and specialty clinics in Canada can assist with sourcing this medication for approved patients. Online Canadian pharmacies may also offer this medicine, but verify credentials before ordering.
Frequently Asked Questions (FAQ)
Is Dimethyl fumarate 120 mg available in Canada?
Yes, Dimethyl fumarate 120 mg is available in Canada by prescription and supplied through authorized pharmacies.
What is the price of Dimethyl fumarate 120 mg in Canada?
The price varies depending on the pharmacy and insurance coverage. Patients should check with their local pharmacy or healthcare provider for accurate pricing and reimbursement options.
What happens if I miss a dose?
If you miss a dose, take it as soon as you remember unless it is near the time of your next scheduled dose. Do not double the dose to catch up. Contact your healthcare provider for specific instructions.
Where can I find Dimethyl fumarate 120 mg for sale?
This medication is available for sale at licensed pharmacies throughout Canada and can be ordered online from certified pharmacy providers with a valid prescription.
Can I drive while taking Dimethyl fumarate 120 mg?
Dimethyl fumarate may cause dizziness or headache in some patients. If these occur, avoid driving or operating heavy machinery until you know how the medicine affects you.
How long does it take to see results from Dimethyl fumarate 120 mg?
Improvements in relapse frequency and disease progression may take several months. Regular follow-up with your neurologist will monitor your response to treatment.
Can I take Dimethyl fumarate 120 mg with other MS medications?
Combining with other disease-modifying therapies should be done only under strict medical supervision due to potential interactions and increased risk of side effects.
Conclusion
Dimethyl fumarate 120 mg is an effective oral treatment option for managing relapsing Multiple Sclerosis, offering benefits such as reduced relapse rate and neuroprotection. Manufactured by Sun Pharmaceutical Industries Ltd, this medication supports patients in controlling their disease progression when used as prescribed. Proper adherence, regular monitoring, and consultation with healthcare professionals ensure the safe and optimal use of Dimethyl fumarate 120 mg in Canada.
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