What is Isosorbide Mononitrate Prolonged Release 60 mg?
Isosorbide Mononitrate Prolonged Release 60 mg is a prescription medication primarily used for the prevention and management of chest pain, medically known as angina. It belongs to a class of drugs called nitrates that help relax and widen blood vessels, improving blood flow to the heart. Manufactured by AstraZeneca Pharma India Ltd, this prolonged-release formulation ensures a steady release of the active ingredient over time, allowing for more consistent symptom control.
This medication is widely trusted for its effectiveness in reducing the frequency and severity of angina attacks. It is intended for patients who require a controlled, long-lasting approach to managing chest pain and improving their quality of life. Its prolonged-release property also helps maintain therapeutic levels in the bloodstream with less frequent dosing.
Uses of Isosorbide Mononitrate Prolonged Release 60 mg
- Prevention of angina pectoris (chest pain) caused by coronary artery disease
- Reducing the frequency and severity of angina attacks
- Improving exercise tolerance in patients with angina
- Used as part of treatment to prevent heart-related complications associated with poor blood flow
How Isosorbide Mononitrate Prolonged Release 60 mg Works
Isosorbide Mononitrate works by relaxing the smooth muscles in the walls of blood vessels, particularly veins. This relaxation causes the vessels to widen, which decreases the heart’s workload by reducing the amount of blood returning to the heart. Consequently, less oxygen is needed by the heart muscle, helping to prevent chest pain caused by insufficient oxygen supply.
The prolonged-release mechanism allows the medication to be absorbed slowly and steadily into the bloodstream, maintaining effective levels throughout the day. This helps to provide continuous relief from angina symptoms without causing sudden drops in blood pressure.
Benefits of Isosorbide Mononitrate Prolonged Release 60 mg
- Provides sustained relief from angina symptoms
- Improves blood flow to the heart, reducing chest pain episodes
- Enhances exercise capacity and overall heart function
- Convenient once or twice daily dosing due to prolonged-release formulation
- Helps prevent complications related to coronary artery disease
Dosage and Administration
The usual recommended dose of Isosorbide Mononitrate Prolonged Release 60 mg varies depending on the patient’s condition and physician’s advice. Typically, it is taken once or twice daily with a glass of water. Do not crush or chew the tablet as it is designed for prolonged release.
It is important to take the medication at the same time(s) each day to maintain consistent drug levels. Always follow the prescribing doctor’s instructions carefully and never adjust the dose without consulting healthcare professionals.
Who Should Use Isosorbide Mononitrate Prolonged Release 60 mg?
This medicine is recommended for adults diagnosed with:
- Chronic stable angina requiring prevention of frequent chest pain episodes
- Patients who need consistent management of heart-related oxygen deficiency
- Individuals who have difficulty tolerating multiple daily doses of immediate-release nitrates
Who Should Avoid Isosorbide Mononitrate Prolonged Release 60 mg?
The use of this medication is contraindicated in certain conditions, including:
- Patients with severe anemia or low blood pressure
- Those with increased intracranial pressure or head injury
- Individuals hypersensitive to nitrates or any ingredients in the product
- Patients using medications for erectile dysfunction such as sildenafil, due to risk of severe hypotension
- People with cardiogenic shock or severe heart failure without proper medical supervision
Side Effects
- Headache
- Dizziness
- Low blood pressure (hypotension)
- Flushing (warmth or redness of the skin)
- Nausea
- Tachycardia (increased heart rate)
- Fatigue
- Lightheadedness
- Weakness
- Allergic reactions (rare)
Safety Advice
- Inform your doctor about all other medicines you are taking
- Avoid driving or operating heavy machinery if you experience dizziness
- Do not stop the medication suddenly without medical advice
- Do not combine with drugs for erectile dysfunction
- Maintain hydration to reduce risk of low blood pressure
- Seek immediate medical help if symptoms like severe dizziness or chest pain worsen
Drug Interactions
- Phosphodiesterase inhibitors (e.g., sildenafil, tadalafil)
- Other vasodilators and antihypertensive drugs
- Alcohol, which may increase hypotensive effects
- Medications affecting blood pressure regulation
Storage Instructions
Store the tablets in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Do not store above 25°C (77°F). Ensure the container is properly closed after each use to maintain medication effectiveness.
Where to buy Isosorbide Mononitrate Prolonged Release 60 mg in Canada?
Isosorbide Mononitrate Prolonged Release 60 mg is available for purchase at licensed pharmacies across Canada. It may also be obtained through verified online Canadian pharmacies with a valid prescription. Always ensure you buy from reputable sources to guarantee the authenticity and quality of the medication.
Frequently Asked Questions (FAQ)
Is Isosorbide Mononitrate Prolonged Release 60 mg available in Canada?
Yes, this medication is available in Canada through licensed pharmacies and verified online retailers with a prescription.
What is the price of Isosorbide Mononitrate Prolonged Release 60 mg in Canada?
The cost varies depending on the pharmacy and insurance coverage. It is recommended to check with local or online pharmacies for the most accurate pricing.
What happens if I miss a dose?
If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose. Do not double dose to make up for missed doses.
Where can I find Isosorbide Mononitrate Prolonged Release 60 mg for sale?
This medication can be purchased at community pharmacies and through reputable online platforms in Canada with a valid prescription.
Can I drink alcohol while taking Isosorbide Mononitrate Prolonged Release 60 mg?
Alcohol may increase the risk of side effects such as dizziness and low blood pressure. It is advisable to limit or avoid alcohol consumption.
How should I store Isosorbide Mononitrate Prolonged Release 60 mg?
Store it in a cool, dry place away from light and moisture, and keep it out of reach of children.
Is it safe to drive after taking Isosorbide Mononitrate Prolonged Release 60 mg?
This medication can cause dizziness or lightheadedness. Avoid driving or operating machinery until you know how the drug affects you.
Conclusion
Isosorbide Mononitrate Prolonged Release 60 mg is a trusted medication for the management and prevention of angina pectoris. Its prolonged-release formulation provides sustained relief from chest pain by improving blood flow to the heart. Manufactured by AstraZeneca Pharma India Ltd, this medicine offers a convenient and effective treatment option for patients seeking improved heart health and quality of life. Always use under the guidance of a healthcare professional to ensure safety and efficacy.
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